Determine the cross-validation accuracy of Needleman-Wunsch with and without affine gaps and with and without BLOSUM62 matrix for the training.txt datasets in PREFAB. Use match cost of +5 and mismatch cost of -4 when testing without BLOSUM62 and otherwise use the BLOSUM62 matrix. Select the best gap open from the set @go = (-16, -14, -12, -10, -8, -6, -4, -2); and the best gap extension from the set @ge = (-2, -1, -.5, -.1); ## Assignment details ## Submit your Perl scripts by copying them into the directory /afs/cad/courses/bnfo/f18/bnfo/601/001/. For example if your ucid is abc12 then copy your Perl scripts into /afs/cad/courses/bnfo/f18/bnfo/601/001/abc12. Make sure your affine alignment script and the alignment accuracy scripts are also there. Also submit a file that shows the table below and your errors. The numbers below are the mean training error for all methods except affine gaps with BLOSUM62 matrix. Non-affine Affine Match/mismatch 55.8 (-16) 51.2 (-16,-2) BLOSUM62 49.2 (-8) 42.5 (-16,-1)