BNFO 602: Foundations of bioinformatics: Comparative Bioinformatics
Spring 2007

Instructor:
Usman Roshan, GITC 3802
Ph: 973-596-2872
Office hours: Wed 3-5:30
Email: usman@cs.njit.edu

Grading: Course project. This will be a short programming project and a class presentation of the results. The project must be approved by the instructor in advance. The deadline for project approval is Feb 7th. You must have an approved project by this date in order to get a grade for this class. The project can be an implementation of a newly published algorithm or experimental study of new and existing software.

Recommended texts:
Course plan:
   
Topic
Date
Lectures
Phylogenetics
01/17/07
Lecture 1
Sequence alignment
01/24/07
Lecture 2
Sequence alignment
01/31/07
Lecture 3
Perl lab
02/06/07
Lecture 4
Class cancelled (NJIT closed due to storm)
02/14/07
Student project proposal presentations
02/21/07
Student project proposal presentations and alignment
02/28/07
Lecture 5
Alignment (HMMs) 03/07/07
Lecture 6
pairwise alignment notes
multiple alignment notes
HMM notes
Alignment
03/21/07
Lecture 7, Lecture 8, Probcons, Probalign
Alignment
03/28/07
Expected accuracy
Project talk
04/04/07
1. Lawrence Drooks: Mutation Detection Probability
2. Dimitrios: A detailed study of the RSmatch algorithm for RNA secondary structure alignment and the correspondent RADAR web-server (paper)
3. Neelam: Neighbor joining additivity and error tolerance proofs
Project talk
04/11/07
1. Sejal: Genome alignment (paper)
2. James: MUMMALS - HMMs with secondary structure states (paper)
3. Devikarani: M-GCAT: interactively and efficiently constructing large-scale multiple genome comparison frameworks in closely related species (paper)
Project talk
04/20/07
1. Joe: Relaxed Neighbor Joining (paper)
2. Ashish: Kalign (paper)
3. Aditya: Prediction of consensus structural motifs in a family of coregulated RNA sequences (paper)
Project talk
04/25/07
1. Justin: Using Phylogeny to Improve Genome-Wide Distant Homology Recognition (paper)
2. Harhsa: Performance evaluation of clustering algorithms for gene expression data (paper)
3. Bhavneet:
4. Kartik: T-coffee (paper)
Project talk
05/02/07
1. Mohan:
2. Anuradha:
3. Deepti: