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NJIT Mathematical Biology Seminar
Monday, April 14, 2008, 11:30pm
Cullimore Hall 611
New Jersey Institute of Technology
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A novel population model for NREM/REM sleep regulation
University of Michigan
In sleep/wake regulatory neuronal populations, microdialysis and microinjection experiments suggest that neurotransmitter dynamics play an important role in the initiation and maintenance of different behavioral states. However, traditional population firing-rate models include synaptic coupling terms without explicitly modeling the dynamics of neurotransmitter concentrations acting at these synapses. We investigate the mechanisms governing NREM/REM sleep regulation using a novel population modeling framework to capture the dynamic interplay between population activity and neurotransmitter concentrations.
Last Modified: Nov 28, 2007
Horacio G. Rotstein
h o r a c i o @ n j i t . e d u
Last modified: Wed Mar 26 12:56:38 EDT 2008