Download and place all scripts in the same directory before executing.

M. Oh, S. Zhao, V. Matveev and F. Nadim (2012)
Neuromodulatory changes in short-term synaptic dynamics may be mediated by two distinct mechanisms of presynaptic calcium entry. Journal of Computational Neuroscience. Epub ahead of print.   PDF     Full Text  


 sweepGsynRandModel1.m Generate optimal parameter sets for Model 1, by fitting data contained in file data.txt
 sweepGsynRandModel2.m Generate optimal parameter sets for Model 2, by fitting data contained in file data.txt
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 AnalyzeResultsModel1.m Generates Fig. 3 based on data in file DataRandGsynModel1.m produced by sweepGsynRandModel1.m
 AnalyzeResultsModel2.m Generates Fig. 6 based on data in file DataRandGsynModel2.m produced by sweepGsynRandModel2.m
 AnalyzeResultsGradient.m Generates Figs. 2 & 5 based on data in files DataRandGsynModel1.m and DataRandGsynModel2.m
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 FitCostGsynModel1.m Calculate objective function for model 1
 FitCostGsynModel2.m Calculate objective function for model 2
 costBalancedInfo.m Lowest-level objective function fitting the time-course and short-term plasticity
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 getData.m Utility data-processing routine
 extract.m Utility data-processing routine
 data.txt Experimental membrane potential time course
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 DataRandGsynModel1.m Example output data: optimal parameter sets for Model 1 produced by sweepGsynRandModel1.m
 DataRandGsynModel2.m Example output data: optimal parameter sets for Model 2 produced by sweepGsynRandModel2.m



Supported in part by the National Science Foundation grant DMS 0817703 to Victor Matveev
Victor Matveev
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Last modified: Aug 19, 2012