Fall 2012 Course Syllabus:  Math 659

Course Title:

Survival Analysis

Textbook:

Survival Analysis: Techniques for Censored and Truncated Data,  by John P. Klein and Melvin L. Moeschberger; Publisher: Springer, 2nd edition (2003); ISBN-13: 978-0387953991.

Reference Books:

# Survival Analysis: A Self-Learning Text, by David G. Kleinbaum and Michael Kline (2005, 2nd Ed.). Survival Analysis Using S: Analysis of Time-to-Event Data, by Mara Tableman and Jong Sung Kim (2003).

Prerequisites:

Math 665 or equivalent with Departmental approval.

 Course Outline Date Lecture Sections Topic Assignment Week 1 9/4 1 Sections 2.1 Lecture Note Introduction to Survival Analysis Introduction to R programming Week 2 9/11 2 Sections 2.2-2.6 Basic Quantities of Survival Time Basic Models for Survival Data Homework 1 Week 3 9/18 3 Sections 3.1-3.5 Censoring and Truncation Week 4 9/25 4 Sections 4.1-4.3 Nonparametric Estimation Methods (I) Homework 2 Week 5 10/2 5 Sections 4.4, 4.6, 5.2 Nonparametric Estimation Methods (II) Week 6 10/9 6 Sections 7.1-7.2 Hypothesis Testing (I) Homework 3 Week 7 10/16 7 Sections 7.3 - 7.4 Hypothesis Testing (II) Week 8 10/23 MIDTERM EXAM: Tuesday ~ October 23, 2011 Week 9 10/30 8 Sections 7.5, 8.1-8.3 Hypothesis Testing (III) Semiparametric Proportional hazards regression models and methods (I) Survival Data Analysis Project Homework 4 Week 10 11/6 9 Sections 8.4 -8.5 Semiparametric Proportional hazards regression models and methods (II) Week 11 11/13 10 Sections 8.7, 9.1 Semiparametric Proportional hazards regression models and methods (III) Refinements of the Semiparametric Proportional Hazards Model (I) Homework 5 Week 12 11/20 11 NO CLASS ~ Follow a Thursday Schedule Week 13 11/27 12 Sections 9.2-9.4 Refinements of the Semiparametric Proportional  Hazards Model (II) Homework 6 Week 14 12/4 13 Sections 11.1-11.4 Regression Diagnostics Week 15 12/11 14 Students’ Project Presentation Week 16 12/18 FINAL EXAM: Tuesday ~ December 18, 2012

 IMPORTANT DATES FIRST DAY OF SEMESTER September 4, 2012 LAST DAY TO WITHDRAW November 6, 2012 LAST DAY OF CLASSES December 12, 2012 FINAL EXAM PERIOD December 14 – 20, 2012

 Assignment Weighting Tentative Grading Scale Homework 25 % A 90 -- 100 Project 20 % B+ 85 -- 90 Midterm Exam 25 % B 80 -- 85 Final Exam 30 % C+ 75 -- 80 C 70 -- 75 F 0 -- 70

Important Departmental and University Policies

Prepared by Prof. Wenge Guo, May 2, 2012