Numerical and Experimental Approaches to Protein Separation and Purification

The biggest problem in biopharmaceutical and industrial protein production at commercial scale is the time and cost associated with separation and purification.
The world market for biopharmaceuticals is about $30 billion and growing at a rate of 20-25% annually. Approximately 80% of these products are proteins whose market
introduction requires extensive attention to isolation and purification methods. The opportunity cost in lost revenues associated with six-month delay in market
introduction of a new drug is enormous. We are developing a novel approach to improving the efficiency, yield, time to scale of biopharmaceutical protein purification that relies on the symbiotic combination of rational and empirical strategies.
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