Microwave Induced Reactions
This teaching manual comprises of
chemistry experiments based on reactions that are induced by microwave.
The reactions are carried out in a microwave similar to one used for
cooking. Microwaves are electromagnetic radiation in the 0.3-300 GHz
frequency range (corresponding to 0.1-100 cm wavelength). To avoid
interference with communication networks, all microwave heaters
(domestic or scientific) are designed to work at either 2.45 GHz or 0.9
GHz, of which, the former is more prevalent. The energy of microwave
radiation is insufficient for molecular excitation, thus most of the
energy is used in substrate heat-up. The mechanism of microwave heating
is different from that of conventional heating, where heat is
transferred by conduction, convection or radiation. In microwave
heating, electromagnetic energy is transformed into heat through ionic
conduction and the friction due to rapid reorientation of the dipoles
under microwave radiation. The larger the dipole moment of a molecule,
the more vigorous is the oscillation in the microwave field,
consequently more heating. This type of heating is fast, has no inertia,
and is in-situ without heating the surroundings.
Chemistry under microwave radiation is known to be
quite different, fast and efficient . It also reduces the need for
solvents, thus it is eco-friendly. It has been exploited in a variety
of organics synthesis including hetero cyclic, organ metallic, and
combinatorial chemistry. Some of the reported advantages are rapid
reactions under controlled temperature and pressure (especially in a
closed system), higher purity products achieved due to short residence
times at higher temperatures, and better yields at even very short
residence times.
Solvents for
Microwave Experiments
Typically all polar solvents which have OH bonds can
absorb microwave radiation. Usually polar solvents includes, water,
acids, alcohols, and amides. The polarities of these compounds are in
the following order:
Water > Acids > Amides > Alcohols
S. No: |
List of Solvents |
1 |
Water |
2 |
Acetic acid |
3 |
Ethanol |
4 |
Isopropanol |
5 |
Formic Acid |
6 |
Acetonitrile |
Microwave
Theory and Lab Manual |