Farinas Laboratory

Research interest: The central aims of our research are to develop methodologies and “rules” for enzyme design, and apply these methods to efficiently create novel and practical biocatalysts. Our current research interests are in engineering proteins using directed evolution and rational approaches. Our research goals include developing high-throughput screening technologies to assay mutant enzyme libraries to discovery novel biocatalyst, combine rational and directed evolution approaches to create de novo enzymes, metabolic pathway engineering in bacteria, novel protein display technologies, and incorporation of nonnatural amino acids in proteins.