Refereed journal articles

15. Directed evolution of CotA laccase for increased substrate specificity using Bacillus subtilis spores. Nirupama Gupta and Edgardo T. Farinas, Protein Engineering Design and Selection, 2010, 23, 679-682.

14. Laboratory evolution of laccase for substrate specificity. Nirupama Gupta, Frederick S. Lee, Edgardo T. Farinas, Journal of Molecular Catalysis B: Enzymatic, 2010, 62, 230-234.

13. Narrowing Laccase Substrate Specificity Using Active Site Saturation Mutagenesis. Nirupama Gupta and Edgardo T. Farinas, Combinatorial Chemistry & High Throughput Screening, 2009, 12, 269-274.

12. Colorimetric high-throughput assay for alkene epoxidation catalyzed by cytochrome P450BM-3 variant 139-3 .Miguel Alcalde*, Edgardo T. Farinas*, Frances H. Arnold Journal of Biomolecular Screening, 2004, 9, 141-146.

*These author contributed equally

11. Alkene epoxidation catalyzed by cytochrome P450 BM-3 139-3. Edgardo T. Farinas, Miguel Alcalde, and Frances Arnold, Tetrahedron, 2003, 60, 525-528.

10. Laboratory Evolution of a soluble, self-sufficient, highly active alkane hydroxylase. Anton Glieder*, Edgardo T. Farinas*, Frances H. Arnold. Nature Biotechnology, 2002, 20, 1135-1139.

*These author contributed equally

9. Directed Evolution of a Cytochrome P450 Monooxygenase for Alkane Oxidation. Edgardo T. Farinas, Ulrich Schwaneberg, Anton Glieder, Frances H. Arnold. Advanced Synthesis and Catalysis, 2001, 343, 601-606.

8. Cost-effective Whole-cell assay for Laboratory Evolution of Hydroxylases in Escherichia coli. Ulrich Schwaneberg, Christopher Otey, Patrick C. Cirino, Edgardo Farinas, and Frances H. Arnold. Journal of Biomolecular Screening, 2001, 6, 111-118.

7. The de novo design of a Rubredoxin-like Fe site. Edgardo T. Farinas and Lynne Regan. Protein Science, 1998, 7, 1939-1946.

6. Photoinduced Oxidation of Hydrocarbons with Cobalt(III)-alkylperoxy Complexes. Edgardo T. Farinas, Cattien Nguyen, and Pradip K. Mascharak. Inorganica Chimica Acta,1997, 263, 17-21.

5. Photoinduced DNA Cleavage Reactions by Designed Analogues of Co(III)-Bleomycin, The Metalated Core is the Primary Determinant of Sequence Specificity. Edgardo T. Farinas, Jennifer D. Tan, and Pradip K. Mascharak. Inorganic Chemistry, 1996, 35, 2637.

4. Structural Features that Control Oxygen Activation at the Non-Heme Iron Site in Fe(II)-Bleomycin: An Analogue Study. Richard J. Guajardo, Ferman Chavez, Edgardo T. Farinas, and Pradip K. Mascharak. Journal of the American Chemical Society, 1995, 117, 3883.

3. Electron Paramagnetic Resonance Studies on the Formation and Decomposition of the Oxygenated Product of [Co^II(PMA)]⁺, a Synthetic Analogue of Co(II)-Bleomycin. Edgardo T. Farinas, Narayan Baidya and Pradip K. Mascharak. Inorganic Chemistry 1994, 33, 5970.

2. NMR Evidence of Sequence Specific DNA Binding by a Co(III)-Bleomycin Analogue with Tethered Acridine. Jennifer D. Tan, Edgardo T. Farinas, Sheila S. David, and Pradip K. Mascharak. Inorganic Chemistry , 1994, 33, 4295.

1. A Designed Synthetic Analogue of Co(III)-Bleomycin with Enhanced DNA-Binding and Photocleaving Activity. Edgardo T. Farinas, Jennifer D. Tan, Narayan Baidya, and Pradip K. Mascharak. Journal of the American Chemical Society 1993, 115, 2996.

Patent Applied For

1. Cytochrome P450 Monooxygenases. Edgardo T. Farinas, Frances H. Arnold, Ulrich Schwaneberg, Anton Glieder, 7,226,768, 2007

Invited articles/book chapters

6. Fluorescence Activated Cell Sorting for Enzymatic Activity; Combinatorial Chemistry and High Throughput Screening, 2006, 9, 321-328

5. Served as Guest editor for a Special Issue of Combinatorial Chemistry and High Throughput Screening 2006, 9

4. Colorimetric Screen for Aliphatic Hydroxylation by Cytochrome P450 Using p-Nitrophenyl-Substituted Alkanes. Direct Evolution Methods Book II: Methods in Molecular Biology Series. Eds. F. H. Arnold and G. Georgiou. Humana Press, Totowa, New Jersey. 2003, 149-155.

3. Directed Enzyme Evolution. Edgardo T. Farinas, Thomas Bulter, Frances H. Arnold. Current Opinions in Biotechnology, 2001, 12, 545-551.

2. Syntheses, Structures and Reactivities of Designed Analogues of Cobalt(III)-Bleomycins: Insight into the Mechanism of Sequence - specific DNA Cleavage upon Illumination. Edgardo T. Farinas and Pradip K. Mascharak. Proceedings of Indian Academy of Science (Chem. Soc.), 1995, 107, 459.

1. Structure and Reactivity of Fe(II)-SAr Complexes: Relevance to the Active Site Of Isopenicillin N Synthase, Edgardo T. Farinas and Pradip K. Mascharak. ChemTracts. 1995, 7, 33.