Microfluidics
Our group’s research in this area focuses on developing advanced microfluidic technologies to improve tissue engineering, biomaterial testing, and cell culturing. By creating automated, addressable microfluidic platforms, we aim to achieve precise and minimally disruptive control over fluid and cell dynamics in both in vitro and in vivo systems. This includes noninvasive sampling, targeted delivery, and continuous monitoring of biomaterial-tissue interactions in animal models, addressing key challenges like invasive analysis and inconsistent results. A long-term goal is to develop microfluidic scaffolds with active nutrient distribution for complex tissue growth, enhancing efficiency and data reliability while promoting more ethical research practices.
Selected Publications:
- Addressable Microfluidics Technology for Non-Sacrificial Analysis of Biomaterial Implants In Vivo Minh Nguyen, Anh Tong, Mark Volosov, Shreya Madhavarapu, Joseph Freeman and Roman Voronov. Biomicrofluidics 17, 024103, 2023.
- A Minireview of Microfluidic Scaffold Materials in Tissue Engineering Anh Tong and Roman Voronov. Frontiers in Molecular Biosciences 8, 783268, 2022.
- Automated Addressable Microfluidic Device for Minimally Disruptive Manipulation of Cells and Fluids within Living Cultures Anh Tong, Quang Long Pham, Vatsal Shah, Akshay Naik, Paul Abatemarco, and Roman Voronov. ACS Biomaterials Science & Engineering 2020 6 (3), 1809-1820.